EvoVF is a database dedicated to Orthologs of the virulence factors and is designed to collate and classify protein based VFs into distinct families.
It aims to facilitate the systematic comparative analysis of nsVF orthologs from both pathogenic and non-pathogenic organisms, with a focus on evolutionary divergence and its effects on protein structure and function.
Definition
Pathogen-specific VFs (psVFs) : Virulence factors which are
unique to pathogens
Non-specific VFs (nsVFs) : Virulence factors which are found in non-pathogenic
species as well, but may contribute to virulence in pathogens.
Distribution of Viruluence Factors in functional categories